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The Center for Translational Vision Research Distinguished Speaker Series, also known as "Friday Seminars" showcases innovative research across the world. The seminar series has now been expanded to include lectures by experts on topics ranging from Ophthalmology, Genetics, Biochemistry, Neurobiology, Imaging, Computational Sciences to Novel Ophthalmic Treatments.
All talks are hybrid. You can join us in person at
You can also join us by zoom. Zoom link and information are on your right and in the calendar links above.
Learn More About the Distinguished Speaker Series
The major goal of the Imanishi lab is to understand the molecular basis of protein transport and membrane morphogenesis in photoreceptor neurons. Deficiencies in these processes lead to photoreceptor degenerative disorders. By combining imaging and molecular biology methods, we aspire to solve long standing questions regarding the mechanism of photoreceptor degeneration caused by mislocalized rhodopsin. Another critical goal of the laboratory is to develop novel therapeutic strategies for treating inherited blinding disorders.
To accomplish these goals, Imanishi lab focuses on the following areas of research: (1) Morphogenesis and maintenance of membrane structures in photoreceptor neurons; (2) Ciliary protein trafficking and ciliopathy in the retina; (3) Drug discovery for inherited blinding disorders. We apply state of the art imaging technologies such as super-resolution fluorescence microscopy, multiphoton microscopy, and high-contents/high-throughout confocal microscopy to visualize and study the dynamic cellular processes. Moreover, we develop new technologies to study proteome in photoreceptor and other retinal neurons at previously unprecedented spatiotemporal resolution.