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Welcome Message

Our Center for Translational Vision Research at the Gavin Herbert Eye Institute serves as an international leader in advancing research and bolstering the support of investigators pursuing basic and translational sciences relevant to vision. We are bringing together exceptional scientific expertise from within the University, the School of Medicine and other schools, and complementary research programs to advance collaborations that focus on fundamental discoveries in vision research with translational potential. We aim to integrate basic and clinical research, including genetics and pharmacology, in order to develop innovative and accessible therapies for millions robbed of their sight or progressing toward blindness.

Dr. Krzysztof Palczewski


Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia

Tworak A., A. V. Kolesnikov, J.D. Hong, E. H. Choi, J. C. Luu, G. Palczewska, Z. Dong, D. Lewandowski, M. J. Brooks, L. Campello, A. Swaroop, P. D. Kiser, V. J. Kefalov, K. Palczewski. Cell Reports 2023  (in press)

Investigating the role of rhodopsin F45L mutation in mouse rod photoreceptor signaling and survival.

D. Poria, A. V. Kolesnikov, T. J. Lee, D. Salom, K. Palczewski, V. J. Kefalov. eNeuro. 2023

Stress induced aging in mouse eye.

Xu Q, Rydz C, Nguyen Huu VA, Rocha L, Palomino La Torre C, Lee I, Cho W, Jabari M, Donello J, Lyon DC, Brooke R, Horvath S, Weinreb RN, Ju WK, Foik A, Skowronska-Krawczyk D*; (2022). Aging Cell , PMID: 36397653 DOI: 10.1111/acel.13737

Genome-Editing in Treatment of Ocular Diseases.

   Choi E. H., S. Suh, A. E. Sears, R. Holubowicz, A. W. Browne, K. Palczewski. Exp Mol Med. 2023 Aug 1. doi: 10.1038/s12276-023-01057-2

Rhodopsin dimers in the Retinal Rod Outer Segment. In “Cryo-electron microscopy in structural biology”

Gulati, S., K. Palczewski.Taylor & Francis Group., CRC Press, Inc. Boca Raton, Florida, USA (in press)

A short story on how chromophore is hydrolyzed from rhodopsin for recycling.

   Hong, J. D. and K. Palczewski. Bioessays. 2023 Jul 16:e2300068.

Saving eyesight, one gene at a time.

   Hołubowicz R, Palczewski K. Trends Mol Med. 2023 May 9:S1471-4914(23)00090-4. doi: 10.1016/j.molmed.2023.04.008