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Distinguished Speaker Series | Philip Kiser, PharmD, PhD

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Location
https://ucihealth.zoom.us/j/94483669170?pwd=WUd1clg2aUM1bnpPVHd3MlkwTUN1Zz09
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The Center for Translational Vision Research Distinguished Speaker Series, also known as "Friday Seminars" showcases innovative research across the world. The seminar series has now been expanded to include lectures by experts on topics ranging from Ophthalmology, Genetics, Biochemistry, Neurobiology, Imaging, Computational Sciences to Novel Ophthalmic Treatments.

All talks are hybrid. You can join us in person at the Gavin Herbert Eye Institute Building, 3d floor Conference Room.

You can also join us by zoom. Zoom link and information are on your right and in the calendar links above.

June 7, 2024 |  Philip Kiser, PharmD, PhD

Dissecting the cell-specific roles of cellular retinaldehyde-binding (CRALBP) protein in photoreceptor function

 

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Philip Kiser, PharmD, PhD
Philip Kiser, PharmD, PhD
  • Associate Professor, Physiology & Biophysics, Joint appointment Ophthalmology University of California, Irvine

Kiser lab is centered on various aspects of the visual cycle pathway that regenerates visual chromophore for the photoreceptor opsins. Dr. Kiser uses an array of experimental techniques and methodologies, including X-ray crystallography, spectroscopy, enzyme kinetics, knockout mouse models, histological and in vivo structural characterization, and biochemical and pharmacological approaches to answer important questions about the structure and function of visual cycle proteins. Major emphasis is placed on the use of such information to develop effective therapeutics for currently untreatable retinal diseases. The laboratory also has a major interest in enzymes involved in carotenoid metabolism.