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Welcome Message

Our Center for Translational Vision Research at the Gavin Herbert Eye Institute serves as an international leader in advancing research and bolstering the support of investigators pursuing basic and translational sciences relevant to vision. We are bringing together exceptional scientific expertise from within the University, the School of Medicine and other schools, and complementary research programs to advance collaborations that focus on fundamental discoveries in vision research with translational potential. We aim to integrate basic and clinical research, including genetics and pharmacology, in order to develop innovative and accessible therapies for millions robbed of their sight or progressing toward blindness.

Palczewski NAS

News

Engineered nucleocytosolic vehicles for loading of programmable editors

Geilenkeuser, J., N. Armbrust, E. Steinmaßl, S. W. Du, S. Schmidt, E. Binder, Y. Li, N.s Warsing, S. V. Wendel, F. von der Linde, E. Schiele, X. Niu, L. Stroppel, O. Berezin, T. Santl, T. Orschmann, K. Nelson, C. Gruber, G. Palczewska, C. Menezes, E. Risaliti, Z. Engfer, N. Koleci, A. Schmidts, A. Geerlof, K. Palczewski, G. G. Westmeyer, D. J. Truong. Cell (2025) in press.

Photopic flicker optoretinography captures the light-driven length modulation of photoreceptors during phototransduction

Tomczewski S, Curatolo A, Foik A, Węgrzyn P, Bałamut B, Wielgo M, Kulesza W, Galińska A, Kordecka K, Gulati S, Fernandes H, Palczewski K, Wojtkowski M. Proc Natl Acad Sci U S A. 2025 Feb 18;122(7):e2421722122. doi: 10.1073/pnas.2421722122. Epub 2025 Feb 13.PMID: 39946535

Insights into the Activation and Self-Association of Arrestin-1

Salom D, Kiser PD, Palczewski K. Biochemistry. 2025 Jan 21;64(2):364-376. doi: 10.1021/acs.biochem.4c00632. Epub 2024 Dec 20. PMID: 39704710; PMCID: PMC11784764.

Integrin Trafficking, Fibronectin Architecture, and Glomerular Injury upon Adiponectin Receptor 1 Depletion

Lindfors S, Schmotz C, Lewandowski D, Hau A, Saikko L, Lehtonen E, Majaniemi V, Karhe M, Naams JB, Nisen H, Tienari J, Saleem MA, Pfeil K, Bugger H, Pietiläinen KH, Mirtti T, Palczewski K, Lehtonen S. J Am Soc Nephrol. 2025 Jan 28. doi: 10.1681/ASN.0000000611. Epub ahead of print. PMID: 39874092.