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May 08, 2024 | UCI School of Medicine
Congratulations to our 2024 Awardees
David Salom, PhD is announced to be the winner of the 2024 UCI School of Medicine Outstanding Career Scientist Research Award! Emily Tom, MD, PhD student received the 2024 Outstanding Graduate Student Research Award Honorable Mention! Congratulations, CTVR members, we are very proud!
Apr 24, 2024 | Center for Translational Vision Research
Dr. Kaipa Awarded the Knights Templar Foundation Grant
Newly received grant from the Knights Templar Foundation Grant will support Dr. Kaipa's research on targeted treatment and the underlying pathophysiology of glaucoma, with a primary focus on the trabecular meshwork (TM).
Mar 28, 2024 | UCI School of Medicine
UCI researchers find potential new gene-independent therapy for retinal degeneration
A research team led by the UC Irvine School of Medicine has identified a potential new gene-independent therapeutic strategy for treating the millions of people worldwide who suffer from retinal degeneration, a group of diseases that can lead to vision loss.
Feb 15, 2024 | Center for Translational Vision Research
Nature Publication - CTVR researchers have crystallized NinaB
CTVR researchers have crystallized the visual chromophore-producing “isomerooxygenase”, NinaB, a key enzyme in the de novo generation of 11-cis-retinal for invertebrate vision. NinaB operates similarly to another protein of major importance for human vision, RPE65, and both belong to the carotenoid cleavage dioxygenase family.
Jan 19, 2024 | Broad Institute
Researchers engineer in vivo delivery system for prime editing, partially restoring vision in mice
Prime editing, a versatile form of gene editing that can correct most known disease-causing genetic mutations, now has a new vehicle to deliver its machinery into cells in living animals. Dr. Liu and his colleagues, in collaboration with Krzysztof Palczewski of the University of California, Irvine, first tested the system in mice to correct two different genetic mutations in the eyes.
Jan 18, 2024 | Center for Translational Vision Research
Philip Kiser, PhD, PharmD has been awarded the Career Advancement Award from RPB
Congratulations to Philip Kiser, PhD, PharmD, who has been awarded the Career Advancement Award from RPB to study the structure and physiology of a protein called cellular retinaldehyde-binding protein (CRALBP).
Jan 17, 2024 | UCI School of Medicine
School of Medicine receives prestigious grant from Research to Prevent Blindness
The University of California, Irvine School of Medicine has received a prestigious Unrestricted Grant from the nonprofit organization Research to Prevent Blindness. The five-year, $575,000 grant will support eye research conducted by the Department of Ophthalmology.
Sep 25, 2023 | Drug Discovery News
A vision of the future: Stem cells offer hope for retinal degeneration
Please read the article based on Dr. Seiler's interview on her groundbreaking research that cell therapies derived from stem cells could one day prevent vision loss or even restore sight in retinal degenerative disease.
Aug 29, 2023 | UCI School of Medicine
UC Irvine researchers discover a nanobody which may lead to treatment for Retinitis Pigmentosa
A special antibody derived from llamas — called a nanobody — can stop the misfolding and the activation of Rhodopsin, a molecule whose mutations can lead to blindness.
Jul 05, 2023 | Center for Translational Vision Research
Distinguished Senior Faculty Award for Research
The Academic Senate has selected Dr. Palczewski to receive the 2023-2024 Distinguished Senior Faculty Award for Research. Dr. Palczewski's compelling and groundbreaking work in advancing our understanding of the retina, especially with respect to phototransduction in the retina, has brought great credit to the university. Congratulations!