New Publication from the Skowronska-Krawczyk Lab

New research from Dr. Skowronska-Krawczyk lab suggests aging is an important component of retinal ganglion cell death in glaucoma, and that novel pathways can be targeted when designing new treatments for glaucoma patients. The study, titled, “Stress induced aging in mouse eye,” was published today in Aging Cell. Along with her colleagues, Dorota Skowronska‐Krawczyk, PhD describes the transcriptional and epigenetic changes happening in aging retina. The team shows how stress, such as intraocular pressure (IOP) elevation in the eye, causes retinal tissue to undergo epigenetic and transcriptional changes similar to natural aging. And, how in young retinal tissue, repetitive stress induces features of accelerated aging including the accelerated epigenetic age.