New Paper Published “Inhibition of ceramide accumulation in AdipoR1-/- mice increases photoreceptor survival and improves vision”

A new paper was published Jan. 11, 2022, titled “Inhibition of ceramide accumulation in AdipoR1-/- mice increases photoreceptor survival and improves vision.” The research highlighted the importance of ADIPOR1 ceramidase in the retina and showed that pharmacological inhibition of ceramide generation can provide a therapeutic strategy for ADIPOR1-related retinopathy.

The study’s authors include: Dominik Lewandowski, Andrzej Foik, Roman Smidak, Elliot H. Choi, Jianye Zhang, Thanh Hoang, Aleksander Tworak, Susie Suh, Henri Leinonen, Zhiqian Dong, Antonio F. M. Pinto, Emily Tom, Jennings Luu, Joan Lee, Xiuli Ma, Erhard Bieberich, Seth Blackshaw, Alan Saghatelian, David C. Lyon, Dorota Skowronska-Krawczyk, Marcin Tabaka, and Krzysztof Palczewski.